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2000 ).This showed a reduction in the annual numbersof neonatal ECMO support from 1991 onwardswhich coincided with an increased use of HFOVand iNO. Extracellular, densely staining, PAS-positivematerial calledCall-Exner bodies (see Fig. Secretes progesterone and estrogen after ovulation5. Leukocytosis (>11giga/l) is observed in only one-third of the patients. In two prospective com-parisons involving PICU patients with respira-tory failure requiring mechanical ventilation,TC-CO2 was signi?cantly closer to arterial PO2values than the simultaneously measured ET-CO2value (Tobias and Meyer 1997b; Berkenboschet al.

The i.o.t.rises rapidly to very high values (40–60 mmHg).It is an emergent condition with marked congestionof eyes and severe headache.

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